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See also:ABSCESS (from See also:Lat. abscedere, to See also:separate) , in See also:pathology, a collection of pus among the tissues of. the See also:body, the result of bacterial inflammation . Without the presence of septic See also:organ-isms See also:abscess does not occur . At any See also:rate, every acute abscess contains septic germs, and these may have reached the inflamed See also:area by See also:direct infection, or may have been carried thither by the See also:blood-stream . Previous to the formation of abscess some-thing has occurred to See also:lower the vitality of the affected tissuesome See also:gross injury, perchance, or it may be that the See also:power of resistance against bacillary invasion was lowered by See also:reason of constitutional weakness . As the result, then, of lowered vitality, a certain area becomes congested and effusion takes See also:place into the tissues . This effusion coagulates and a hard, brawny See also:mass is formed which softens towards the centre . If nothing is done the softened area increases in See also:size, the skin over it becomes thinned, loses its vitality (mortifies) and a small " See also:slough " is formed . When the slough gives way the pus escapes and, tension being relieved, See also:pain ceases . A See also:local See also:necrosis or See also:death of See also:tissue takes place at that, See also:part of the inflammatory swelling farthest from the healthy circulation . When the attack of septic inflammation is very acute, death of the tissue occurs en masse, as in the core of a See also:boil or See also:carbuncle . Sometimes, however, no such mass of dead tissue is to be observed, and all that escapes when the skin is lanced or gives way is the creamy pus . In the latter See also:case the tissue has broken down in a molecular See also:form . 'After the See also:escape of the core or slough along with a certain amount of pus, a space; the abscess-cavity, is See also:left, the walls of which are lined with new vascular tissue which has itself escaped destruction .. This lowly organized material is called granulation tissue, and exactly resembles the growth which covers the See also:floor of an See also:ulcer . These granulations eventually fill the contracting cavity and obliterate it by forming interstitial scar-tissue . This is called healing by second intention . Pus may accumulate in a normal cavity, such as a See also:joint or bursa, or in the See also:cranial, thoracic or abdominal cavity . In all these situations, if the diagnosis is clear, the principle of treatment is evacuation and drainage . When evacuating an abscess it is often advisable to scrape away the lining of unhealthy granulations and to See also:wash out the cavity with an antiseptic lotion . If the after-drainage of the cavity is thorough the formation of pus ceases and the watery See also:discharge from the abscess See also:wall subsides . As the cavity contracts the discharge becomes less, until at last the drainage See also:tube can be removed and the See also:external See also:wound allowed to heal . The large collections of pus which form in connexion with disease of the See also:spinal See also:column in the cervical, dorsal and lumbar regions are now treated by See also:free evacuation of the tuberculous pus, with careful antiseptic See also:measures . The opening should be in as de-pendent a position as possible in See also:order that the drainage may be thorough . If tension recurs after opening has been made, as by the blocking of the tube, or by its imperfect position, or by its being too See also:short, there is likely to be a fresh formation of pus, and without delay the whole See also:procedure must be gone through again . (E . |
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