ACROMEGALY  , the name given to a disease characterized by a true

hypertrophy (an overgrowth involving both bony and soft parts) of the terminal parts of the body, especially of the face and extremities (Gr. arcpov, point, and tcEyas, large) . It is more frequent in the female sex, between the ages of 25 and 40 . Its causation is generally associated with disturbances in the pituitary gland, and an extract of this body has been tried in the treatment, as one of the recent developments in organotherapeutics; thyroid extract has also been used, but without marked success, on the apparent analogy of acromegaly with myxoedema .