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See also: malaria (q.v.)
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It is characterized by irregular febrile paroxysms, accompanied by rigors, bilious vomiting, jaundice and haemoglobinuria (Sambon)
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It has a wide See also: geographical distribution, including tropical See also: Africa, parts of See also: Asia, the West Indies, the See also: southern See also: United States, and—in Europe—Greece, See also: Sicily and See also: Sardinia; but its range is not coextensive with malaria
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Malarial parasites have occasionally been found in the See also: blood
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Some authorities believe it to be caused by the excessive use of See also: quinine, taken to combat malaria
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This theory has had the support of See also: Koch, but it is not generally accepted
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If it were correct, one would expect See also: blackwater fever to be regularly prevalent in malarial countries and to be more or less coextensive with the use of quinine, which is not at all the See also: case
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It often resembles yellow fever, but the characteristic black vomit of yellow fever rarely occurs in blackwater fever, while the black urine from which the latter derives its name is equally rare in the former
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According to the See also: modern school of tropical parasitology, blackwater fever is neither a See also: form of malaria nor, produced by quinine, but a specific disease due to a protozoal parasite akin to that which causes the redwater fever of cattle
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Black water fever is not extinct yet. It is associated with haemoglobinuria due to massive haeolysis- most commonly due to malaria. It is more common with G6PD deficient prsons. Th euse of quinine can be replaced with artemisisnine derivatives like artesunate or artemether. Unless hydration is taken care of and the renal functions, it may lead o renal failure and even death.
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