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See also:FIBRIN, or FIBRINE , a protein formed by the See also:action of the so-called See also:fibrin-ferment on fibrinogen, a constituent of the See also:blood-plasma of all vertebrates . This See also:change takes See also:place when blood leaves the See also:arteries, and the fibrin thus formed occasions the clotting which ensues (see BLOOD) . To obtain pure coagulated fibrin it is best to See also:heat blood-plasma (preferably that of the See also:horse) to 56° C . The usual method of beating a blood-See also:clot with twigs and removing the filamentous fibrin which attaches itself to them yields a very impure product containing haemoglobin and much globulin; moreover, it is very difficult to purify . Fibrin is a very voluminous, tough, strongly elastic, jelly-like substance; when denaturalized by heat, See also:alcohol or salts, it behaves as any other coagulated See also:albumin . |
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