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HIPPURIC See also:ACID (Gr. iazros, See also:horse, ovpov, urine) , benzoyl glycocoll or benzoyl amidoacetic See also:acid, C9H9NO3 or C6H5CO NH•See also:CH2•See also:CO2H, an organic acid found in the urine of horses and other herbivorae . It is excreted when many aromatic compounds, such as benzoic acid and See also:toluene, are taken internally . J. v . See also:Liebig in 1829 showed that it differed from benzoic acid, and in 1839 determined its constitution, while in 18J3 V . Dessaignes (See also:Ann . 87, p . 325) synthesized it by acting with benzoyl chloride on See also:zinc glycocollide . It is also formed by See also:heating benzoic anhydride with glycocoll (Th . See also:Curtius, Ber., 1884, 17, p . 1662), and by heating benzamide with monochloracetic acid . It crystallizes in rhombic prisms which are readily soluble in hot See also:water, melt at 187° C. and decompose at about 2400 C . It is readily hydrolysed by hot See also:caustic alkalis to benzoic acid and glycocoll . Nitrous acid converts it into benzoyl glycollic acid, See also:C6H,CO.O•CH2•CO2H . Its See also:ethyl ester reacts with See also:hydrazine to See also:form hippuryl hydrazine, C6H5CO•NH•CH2•CO•NH•See also:NH2, which was used by Curtius for the preparation of See also:azoimide (q.v.) . |
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