C8H5NO2 See also:

• C8H5NO2 ISATIN

ISATIN  , in See also:

• CHEMISTRY
• CHEMISTRY (formerly "chymistry"; Gr. xvµela; for derivation see ALCHEMY)

chemistry, a derivative of indol, interesting on See also:

• ACCOUNT
• ACCOUNT (through O. Fr. acont, Late Lat. comptum, cornputare, to calculate)

account of its relation to See also:

• INDIGO (earlier indico, from Lat. indicum, the Indian sub-stance or dye; the Sans. name was niti, from nila, dark blue, and this through Arab. al-nil, annil, gives " aniline ")

indigo; it may be regarded as the anhydride of ortho-aminobenzoylformic or isatinic See also:

• ACID (from the Lat. root ac-, sharp; acere, to be sour)

acid . It crystallizes in See also:

• ORANGE
• ORANGE (Citrus Aurantium)
• ORANGE, HOUSE OF

orange red prisms which melt at 200-201° C . It may be prepared by oxidizing indigo with nitric or chromic acid (0 . L . See also:

• ERDMANN
• ERDMANN, JOHANN EDUARD (1805-1892)

Erdmann, Jour. prak . Chem., 1841, 24, p . 11); by boiling ortho-nitrophenylpropiolic acid with alkalis (A . See also:

• BAEYER, JOHANN FRIEDRICH WILHELM ADOLF VON (1835– )

Baeyer, Ber., 188o, 13, p . 2259), or by oxidizing carbostyril with alkaline See also:

• POTASSIUM [symbol K (from kalium), atomic weight 39.114 0=16)]

potassium permanganate (P . Friedlander and H . Qstermaier, Ber., 1881, 14, p . 1921) .

P . J . See also:

• MEYER, CHRISTIAN ERICH HERMANN VON (18or-1869)
• MEYER, HEINRICH AUGUST WILHELM (1800-1873)
• MEYER, JULIUS LOTHAR (183o-1895)
• MEYER, KONRAD FERDINAND (1825-1898)
• MEYER, VICTOR (1848-1897)
• MEYER, [MARIE] PAUL HYACINTHE (184o- )

Meyer (See also:

• GERMAN
• GERMAN, DUTCH AND SCANDINAVIAN

German Patent 26736 (1883)) obtains substituted isatins by condensing See also:

• PARA
• PARA (officially BELEM; sometimes BELEM DO PARA)

para-toluidine with dichloracetic acid, oxidizing the product with See also:

• AIR (from an Indo-European root meaning " breathe," " blow ")
• AIR, or ASBEN

air and then hydrolysing the oxidized product with hydrochloric acid . T . Sandmeyer (German See also:

• PATENTS

Patents 113981 and 119831 (1899)) obtained See also:

• ISATIN, C8H5NO2

isatin-a-anilide by condensing See also:

• ANILINE, PHENYLADIINE, or AMINOBENZENE, (C6H5NH2)

aniline with See also:

• CHLORAL

chloral See also:

• HYDRATE

hydrate and See also:

• HYDROXYLAMINE, NH2OH

hydroxylamine, an intermediate product isonitrosodiphenylacetamidine being obtained, which is converted into isatin-aanilide by sulphuric acid . This can be converted into indigo II by reduction with ammonium sulphide . Isatin dissolved in concentrated sulphuric acid gives a See also:

• BLUE (common in different forms to most European languages)

blue coloration with thiophene, due to the formation of indophenin (see Abst . J.C.S., 1907) . Concentrated nitric acid oxidizes it to oxalic acid, and See also:

• ALKALI

alkali See also:

• FUSION

fusion yields aniline . It dissolves in soda forming a See also:

• VIOLET

violet See also:

• SOLUTION (from Lat. solvere, to loosen, dissolve)

solution, which soon becomes yellow, a See also:

• CHANGE (derived through the Fr. from the Late Lat. cambium, cambiare, to barter; the ultimate derivation is probably from the root which appears in the Gr. «a urmu', to bend)

change due to the transformation of See also:

• SODIUM [symbol Na, from Lat. natrium; atomic weight 23.00 (0=16)]

sodium N-isatin into sodium isatate, the aciisatin See also:

• SALT (a common Teutonic word, cf. Dutch zout, Ger. Salz, Scand. salt; cognate with Gr. &Xs, Lat. sal)
• SALT, SIR TITUS, BART

salt being probably formed intermediately (See also:

• HELLER, STEPHEN (181 1888)

Heller, Abst . J.C.S., 1907, i. p . 442) .

Most metallic salts are N-derivatives yielding N-methyl See also:

• ETHERS

ethers; the See also:

• SILVER

silver salt is, however, an 0-derivative, yielding an 0-methyl See also:

• ETHER, (C2H5)2O

ether (A. v . Baeyer, 1883; W . See also:

• PETERS (or PETER), HUGH (1598–166o)
• PETERS, KARL (1856– )

Peters, Abst . J.C.S., 1907, i. p . 239) .