See also:MYXOEDEMA (or athyrea)
, the medical See also:term for a constitutional disease (see METABOLIC DISEASES) due to the degeneration of the See also:thyroid gland, and occurring in adults; it may be contrasted with See also:cretinism, which is a See also:condition appearing in See also:early childhood
.
There are two forms, See also:myxoedema proper and operative myxoedema (cachexia slrumipriva)
.
(1) Myxoedema has been termed " See also:Gull's Disease" from See also:Sir See also:- WILLIAM
- WILLIAM (1143-1214)
- WILLIAM (1227-1256)
- WILLIAM (1J33-1584)
- WILLIAM (A.S. Wilhelm, O. Norse Vilhidlmr; O. H. Ger. Willahelm, Willahalm, M. H. Ger. Willehelm, Willehalm, Mod.Ger. Wilhelm; Du. Willem; O. Fr. Villalme, Mod. Fr. Guillaume; from " will," Goth. vilja, and " helm," Goth. hilms, Old Norse hidlmr, meaning
- WILLIAM (c. 1130-C. 1190)
- WILLIAM, 13TH
William Gull's observations in 1873
.
See also:Women are more often the victims than men, in a ratio of 6 to 1
.
It frequently affects members of the same See also:family and may be transmitted through the See also:mother, and it has been observed sometimes to follow exophthalmic See also:goitre
.
The symptoms are a marked increase in bulk and See also:weight of the See also:body, puffy See also:appearance of skin which does not See also:- PIT (O. E. pytt, cognate with Du. put, Ger. Pfutze, &c., all ultimately adaptations of Lat. puteus, well, formed from root pu-, to cleanse, whence gurus, clean, pure)
pit on pressure, the See also:line of the features becoming obliterated and getting coarse and broad, the lips thick and nostrils enlarged, with loss of See also:hair, subnormal temperature and marked See also:mental changes
.
There is striking slowness of thought and See also:action, the memory becomes defective, and the patient becomes irritable and suspicious
.
In some instances the condition progresses to that of dementia
.
The thyroid gland itself is diminished in See also:size, and may become completely atrophied and converted into a fibrous See also:mass
.
The untreated disease is progressive, but the course is slow and the symptoms may extend over 12 to 15 years, See also:death from asthenia or See also:tuberculosis being the most frequent ending
.
(2) Symptoms similar to the above me y follow See also:complete removal of the thyroid gland
.
Kocher of See also:Bern found that, in the See also:total removal of the gland by operation, out of 408 cases operative myxoedema occurred in 6g, but it is thought that if a small portion of the gland is See also:left, or if See also:accessory glands are See also:present, these symptoms will not develop
.
The treatment of myxoedema is similar to that of cretinism
.
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