See also:willow-bark, discovered by
See also:Leroux in 1831 . It exists in most
See also:species of Salix and Populus, and has been obtained to the extent of 3 or 4% from the bark of S.
See also:helix and S. pentandra .
See also:Salicin is prepared from a decoction o the bark by first precipitating the
See also:tannin by milk of lime, then evaporating the filtrate to a soft extract, and dissolving out the salicin by
See also:alcohol . As met with in commerce it is usually in the
See also:form of glossy
See also:white scales or needles . It is neutral, odourless, unaltered by exposure to the air, and has a bitter taste . It is soluble in about 30 parts of
See also:water and 8o parts of alcohol at the ordinary temperature, and in 0.7 of boiling water or in 2 parts of boiling alcohol, and more freely in alkaline liquids . It is also soluble in acetic acid without alteration, but is insoluble in
See also:chloroform and benzol . From phloridzin it is distinguished by its ammoniacal solution not becoming coloured when exposed to the air . Chemically, it is a
See also:glucoside derived from
See also:glucose and saligenin (o-oxy-benzyl alcohol), into which it is decomposed by the enzymes ptyaline and emulsin . Oxidation converts it into helicin (salicylaldehyde-glucose) . Populin, a benzoyl salicin, is a glucoside found in the leaves and bark of Populus tremula . Salicin is used in
See also:medicine for the same purposes as salicylic acid and the salicylates .
It is also used as a bitter tonic, i.e. a gastric stimulant, in doses of five grains . The ordinary dose may go up to
See also:forty grains or more with perfect safety, though the
See also:British Pharmacopoeia limits it to twenty . The remote
See also:action of the
See also:drug is that of salicylic acid or the numerous compounds that contain it (see SALICYLIC ACID) .
ANTOINE CHRISTOPHE SALICETI (1757-1809)
SALICYLIC ACID (ortho-hydroxybenzoic acid)
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