SANTONIN , a
See also:drug used in the U.S.P. and B.P., consisting'of colourless
See also:flat prisms, turning slightly yellow from the
See also:action of
See also:light and soluble in
See also:chloroform and boiling
See also:water . It is derived from santonica which is the unexpanded flower-heads of Artemisia maritima . The dose is 2 to 5 grs . The only B.P. preparation is the trochiscus santonini, but the preparation sodii santoninas is official in the U.S.P . Santonin is an anthelmintic used to
See also:poison the
See also:worm Ascaris lumbricoides . It has no influence on tape-
See also:worms . It must be administered
See also:fasting and be followed by a purgative in
See also:order to expel the worm . The most convenient mode of administration is in capsules . For
See also:thread worms which infest the anus of
See also:children, a suppository containing 2 to 3 grs. of santonin and used on alternate nights for three nights is effective . The U.S. preparation sodii santoninas is useless as a vermifuge and is used in diseased conditions of the optic nerve . Even small doses of santonin cause disturbances of vision, usually yellow vision or perhaps
See also:green (xanthopsia or chromatopsia) . The urine also turns yellow and finally
See also:purple or red .
These effects usually pass off in a few days . Large doses, however, produce toxic effects, aphasia,
See also:muscular tremors and epileptiform
See also:convulsions, and the disturbances of vision may go on to
See also:blindness .
SANTO DOMINGO [SAN DOMINGO, DOMINICAN REPUBLIC, or ...
SANTORIN (corruption of St Irene; anc. THERA)
the structure of SANTONIN should be drawn in the article and expansions of B.p should be given in the article
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